Power-efficient distributed resource allocation under goodput QoS constraints for heterogeneous networks

This work proposes a distributed resource allocation (RA) algorithm for packet bit-interleaved coded OFDM transmissions in the uplink of heterogeneous networks (HetNets), characterized by small cells deployed over a macrocell area and sharing the same band. Every user allocates its transmission resources, i.e., bits per active subcarrier, coding rate, and power per subcarrier, to minimize the power consumption while both guaranteeing a target quality of service (QoS) and accounting for the interference inflicted by other users transmitting over the same band. The QoS consists of the number of information bits delivered in error-free packets per unit of time, or goodput (GP), estimated at the transmitter by resorting to an efficient effective SNR mapping technique. First, the RA problem is solved in the point-to-point case, thus deriving an approximate yet accurate closed-form expression for the power allocation (PA). Then, the interference-limited HetNet case is examined, where the RA problem is described as a non-cooperative game, providing a solution in terms of generalized Nash equilibrium. Thanks to the closed-form of the PA, the solution analysis is based on the best response concept. Hence, sufficient conditions for existence and uniqueness of the solution are analytically derived, along with a distributed algorithm capable of reaching the game equilibrium

A robust resource allocation algorithm for packet BIC-UFMC 5G wireless communications

In this paper, we present a novel resource allocation (RA) algorithm for packet Universal Filtered Multi-Carrier (UFMC) BIC-based communications, the latter being a novel modulation format possibly envisaged to be applied in 5G wireless systems. Assuming the perfect knowledge of the channel and capitalizing on the specific UFMC signal waveform, the proposed RA strategy optimizes the coding rate and bit loading within the overall bandwidth along with the per-subband power distribution. In the presence of a carrier offset and over fading selective channels, the results we obtained are twofold: i) the UFMC format reveals to be more robust than the conventional OFDM scheme; ii) the performance of the UFMC system itself is further boosted by the optimal choice of radio resources evaluated by the proposed RA algorithm

Cohort profile: the Turin prostate cancer prognostication (TPCP) cohort

IntroductionProstate cancer (PCa) is the most frequent tumor among men in Europe and has both indolent and aggressive forms. There are several treatment options, the choice of which depends on multiple factors. To further improve current prognostication models, we established the Turin Prostate Cancer Prognostication (TPCP) cohort, an Italian retrospective biopsy cohort of patients with PCa and long-term follow-up. This work presents this new cohort with its main characteristics and the distributions of some of its core variables, along with its potential contributions to PCa research.MethodsThe TPCP cohort includes consecutive non-metastatic patients with first positive biopsy for PCa performed between 2008 and 2013 at the main hospital in Turin, Italy. The follow-up ended on December 31st 2021. The primary outcome is the occurrence of metastasis; death from PCa and overall mortality are the secondary outcomes. In addition to numerous clinical variables, the study’s prognostic variables include histopathologic information assigned by a centralized uropathology review using a digital pathology software system specialized for the study of PCa, tumor DNA methylation in candidate genes, and features extracted from digitized slide images via Deep Neural Networks.ResultsThe cohort includes 891 patients followed-up for a median time of 10 years. During this period, 97 patients had progression to metastatic disease and 301 died; of these, 56 died from PCa. In total, 65.3% of the cohort has a Gleason score less than or equal to 3 + 4, and 44.5% has a clinical stage cT1. Consistent with previous studies, age and clinical stage at diagnosis are important prognostic factors: the crude cumulative incidence of metastatic disease during the 14-years of follow-up increases from 9.1% among patients younger than 64 to 16.2% for patients in the age group of 75-84, and from 6.1% for cT1 stage to 27.9% in cT3 stage.DiscussionThis study stands to be an important resource for updating existing prognostic models for PCa on an Italian cohort. In addition, the integrated collection of multi-modal data will allow development and/or validation of new models including new histopathological, digital, and molecular markers, with the goal of better directing clinical decisions to manage patients with PCa

Long-term home ventilation of children in Italy: A national survey.

BACKGROUND: Improved technology, as well as professional and parental awareness, enable many ventilator-dependent children to live at home. However, the profile of this growing population, the quality and adequacy of home care, and patients' needs still require thorough assessment. OBJECTIVES: To define the characteristics of Italian children receiving long-term home mechanical ventilation (HMV) in Italy. METHODS: A detailed questionnaire was sent to 302 National Health Service hospitals potentially involved in the care of HVM in children (aged <17 years). Information was collected on patient characteristics, type of ventilation, and home respiratory care. RESULTS: A total of 362 HMV children was identified. The prevalence was 4.2 per 100,000 (95% CI: 3.8-4.6), median age was 8 years (interquartile range 4-14), median age at starting mechanical ventilation was 4 years (1-11), and 56% were male. The most frequent diagnostic categories were neuromuscular disorders (49%), lung and upper respiratory tract diseases (18%), hypoxic (ischemic) encephalopathy (13%), and abnormal ventilation control (12%). Medical professionals with nurses (for 62% of children) and physiotherapists (20%) participated in the patients' discharge from hospital, though parents were the primary care giver, and in 47% of cases, the sole care giver. Invasive ventilation was used in 41% and was significantly related to young age, southern regional residence, longer time spent under mechanical ventilation, neuromuscular disorders, or hypoxic (ischemic) encephalopathy. CONCLUSIONS: Care and technical assistance of long-term HMV children need assessment, planning, and resources. A wide variability in pattern of HMV was found throughout Italy. An Italian national ventilation program, as well as a national registry, could be useful in improving the care of these often critically ill children

D13.2 Techniques and performance analysis on energy- and bandwidth-efficient communications and networking

Deliverable D13.2 del projecte europeu NEWCOM#The report presents the status of the research work of the various Joint Research Activities (JRA) in WP1.3 and the results that were developed up to the second year of the project. For each activity there is a description, an illustration of the adherence to and relevance with the identified fundamental open issues, a short presentation of the main results, and a roadmap for the future joint research. In the Annex, for each JRA, the main technical details on specific scientific activities are described in detail.Peer ReviewedPostprint (published version

D13.3 Overall assessment of selected techniques on energy- and bandwidth-efficient communications

Deliverable D13.3 del projecte europeu NEWCOM#The report presents the outcome of the Joint Research Activities (JRA) of WP1.3 in the last year of the Newcom# project. The activities focus on the investigation of bandwidth and energy efficient techniques for current and emerging wireless systems. The JRAs are categorized in three Tasks: (i) the first deals with techniques for power efficiency and minimization at the transceiver and network level; (ii) the second deals with the handling of interference by appropriate low interference transmission techniques; (iii) the third is concentrated on Radio Resource Management (RRM) and Interference Management (IM) in selected scenarios, including HetNets and multi-tier networks.Peer ReviewedPostprint (published version

D13.1 Fundamental issues on energy- and bandwidth-efficient communications and networking

Deliverable D13.1 del projecte europeu NEWCOM#The report presents the current status in the research area of energy- and bandwidth-efficient communications and networking and highlights the fundamental issues still open for further investigation. Furthermore, the report presents the Joint Research Activities (JRAs) which will be performed within WP1.3. For each activity there is the description, the identification of the adherence with the identified fundamental open issues, a presentation of the initial results, and a roadmap for the planned joint research work in each topic.Preprin

The MAORY first-light adaptive optics module for E-ELT

The MAORY adaptive optics module is part of the first light instrumentation suite for the E-ELT. The MAORY project phase B is going to start soon. This paper contains a system-level overview of the current instrument design

MAORY: adaptive optics module for the E-ELT

MAORY is one of the four instruments for the E-ELT approved for construction. It is an adaptive optics module offering two compensation modes: multi-conjugate and single-conjugate adaptive optics. The project has recently entered its phase B. A system-level overview of the current status of the project is given in this paper

STRATEGIE DI ALLOCAZIONE DELLE RISORSE IN TRASMISSIONI MULTIPORTANTE A PACCHETTO E CODIFICATE PER RETI WIRELESS 4G-5G

Alta trasmissione dati, vasta area di copertura, alta Quality of Service (QoS) e l’uso efficiente delle risorse di trasmissione sono le principali sfide che devono essere affrontate nella attuale comunicazioni wireless Forth Generation (4G) e soprattutto nella prossima Fifth Generation (5G). La ricerca scientifica ha dimostrato che la tecnica Orthogonal Frequency-Division Multiplexing (OFDM), schemi di codifica avanzate come Bit-Interleaved Coded (BIC), meccanismi di Resource Allocation (RA), Heterogeneous Network (HetNet), tecniche di relay e Cognitive Radio (CR) possono aumentare la trasmissione dati, la copertura radio e l’efficienza spettrale nei sistemi wireless 4G. In parallelo con il lavoro di ricerca nell’ambito 4G, la ricerca e l’industria stanno indirizzando i loro sforzi per fornire nuove soluzioni tecnologiche nell’ambito 5G, infatti una pre-standardizzazione é prevista per il 2020. Nel contesto 5G, l’OFDM potrebbe non essere sempre adatto, soprattutto per quelle applicazioni dove sono strettamente necessari risparmio energetico e latenza “ultra bassa”. Infatti, l’OFDM é caratterizzato da algoritmi di sincronizzazione molto complessi per preservare l’ortogonalitá del segnale e inoltre considera la presenza di un prefisso ciclico nel segnale trasmesso. Questi fattori degradano l’efficienza energetica e aumentano la latenza. Inoltre, elevati livelli di lobi laterali rendono l’OFDM sensibile alle interferenze in caso di spectrum sharing. Di conseguenza, lo studio di nuove forme d’onda per l’interfaccia di accesso radio é una delle sfide principali da affrontare. Uno delle piú promettenti forme d’onda 5G é la Universal Filtered MultiCarrier (UFMC). La modulazione UFMC é in grado di migliorare la robustezza a errori di sincronismo nel tempo e in frequenza, di incrementare l’efficienza spettrale e di ridurre le emissioni fuori banda senza perdere i vantaggi della classica modulazione OFDM. Questa tesi presenta nuove tecniche di RA per sistemi a trasmissione di pacchetti OFDM e UFMC, considerando diversi scenari applicativi: CR, comunicazioni multihop, HetNet e Internet of Thing (IoT). Sulla base di diverse Channel State Information (CSI), le soluzioni di RA presentate hanno lo scopo di allocare la potenza sulle varie sottoportanti del sistema di trasmissione e di selezionare una modulazione e codifica, con lo scopo di massimizzare la metrica del Goodput (GP), definita come il numero di bit di informazione forniti in pacchetti senza errori nell’unitá di tempo